Immunohistochemistry Kits and Reagents
Active Motif MAXwash™ Washing Medium
MAXwash Washing Medium is a proprietary formulation designed and optimized to eliminate non-specific primary and secondary antibody binding. It has been tested and proven effective at eliminating off-target antibody binding in immunofluorescence assays.
Abcam DoubleStain CL IHC Kit: G&Rt on human/mouse tissue (HRP/Green & AP/Red), 60ML
Abcam's Doublestain IHC Kit (ab183282) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Cell Signaling Technology Phospho-FAK (Tyr397) (D20B1) Rabbit Monoclonal Antibody (BSA and Azide Free) 100uug
This product is the carrier free version of product #8556. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
Biotium Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2923), Biotin conjugate, 0.1mg/mL
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like
ABclonal Technology TFF1/pS2 Rabbit mAb
Members of the trefoil family are characterized by having at least one copy of the trefoil motif a 40-amino acid domain that contains three conserved disulfides They are stable secretory proteins expressed in gastrointestinal mucosa Their functions are not defined but they may protect the mucosa from insults stabilize the mucus layer and affect healing of the epithelium This gene which is expressed in the gastric mucosa has also been studied because of its expression in human tumors This gene and two other related trefoil family member genes are found in a cluster on chromosome 21
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Biotium Uroplakin 1A (Urothelial Differentiation Marker)(UPK1A/2924), CF740 conjugate, 0.1mg/mL
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like
FUJIFILM BIOSCIENCES INC Anti Human Podocalyxin Monoclo
Podocalyxin is a member of the CD34 family of type I transmembrane sialomucins It is expressed in many normal cells such as renal podocytes and endothelial cells It is also expressed in many types of tumors including colorectal cancers breast cancers and brain tumors Overexpression of podocalyxin is an independent predictor of progression metastasis and poor prognosis Recent studies indicate that the glycosylation of podocalyxin change depending on the state of the cells This antibody recognized endogenous podocalyxin expressing cancer cell lines and normal cells independently of glycosylation
ABclonal Technology Phospho-SMO-S616 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
Abcam DoubleStain IHC Kit: R&Rt on human/mouse tissue (Green/HRP & AP/Red), 6ML
Abcam's Doublestain IHC Kit (ab183285) is designed for use with user supplied rabbit and rat primary antibodies to detect two distinct antigens on human and mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Desmin Rabbit pAb
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
American Research Products Inc PrEST Antigen IGF2BP1
PrEST Antigen IGF2BP1 antigen APrEST87959 for insulin-like growth factor 2 mRNA binding protein 1 Recombinant protein fragment of Human IGF2BP1
American Research Products Inc PrEST Antigen LRP2
PrEST Antigen LRP2 antigen APrEST88106 for low density lipoprotein receptor-related protein 2 Recombinant protein fragment of Human LRP2
Biotium CD25(IL2RA/423), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes l
Biotium c-Myc(MYC275), CF594 conjugate, 0.1mg/mL
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability.